Given the multifaceted advantages of antibody discovery services and platforms, the field has witnessed an increase in the number of players involved in the development of such solutions. The domain features the presence of over 80 service providers and 124 platform providers which are involved in providing services for antibody discovery. The market is characterized by the presence of small companies / start-ups (up to 50 employees) followed by mid-sized companies (51-500 employees) and large companies (more than 500 employees). Examples of service and platform providers include (in alphabetical order) AbBioSci, Bio-Rad Laboratories and DJS Antibodies.
Majority of the players (94) offer services related to antibody optimization. This step involves modification of the most promising lead compounds to impart drug-like properties to it before it can be selected as a clinical candidate. Of these, 46 companies offer antibody humanization services, 40 offer affinity maturation services while 8 companies offer Fc engineering services. Additionally, it is worth mentioning that five service providers, namely Abveris Antibody, BioDuro Biologics, HD Biosciences, ProteoGenix and Wuxi Biologics serve as one-stop-shop for all the antibody discovery steps mentioned above.
In addition, we came across 37 companies which provide discovery services for both therapeutic and diagnostic antibodies; examples include (in alphabetical order) Aldevron, BIOTEM, Creative Diagnpostics and Syngene. Further, 22 companies provide services for only therapeutic antibodies while five companies provide services for only diagnostic antibodies. Examples include (in alphabetical order) Ab Studio (therapeutic), Accurus Biosciences (therapeutic), ChemPartner (therapeutic), Maine Biotechnology Services (diagnostic), and OriGene Technologies (diagnostic).
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