Diabetic nephropathy or kidney disease

Diabetic nephropathy (CKD) is a form of chronic kidney disease. The kidneys regulate fluid and salt levels in the body. This is essential for maintaining cardiovascular health and controlling blood pressure. Do not use Tadalista 20 when you have this problem.

Diabetes is a condition in which the body can’t use or produce insulin properly. 

These high glucose levels can cause damage to various parts of the body over time, including the kidneys and cardiovascular system. Diabetic nephropathy is the term for kidney damage.

ESRD is a condition in which the kidneys are not working well enough to support daily living. ESRD can cause kidney failure which could lead to serious and potentially fatal consequences.

This article examines how diabetes can impact the kidneys and the available treatment.

Find out more about type 1 diabetes and type 2 diabetes.

What’s diabetic nephropathy?

Nephropathy is a condition that can affect anyone with diabetes. It results from high blood glucose.

High blood sugar levels can cause damage to the arteries and kidneys.

Researchers from Trusted Source 2016 found that between 20 and 40% of diabetics develop some form of kidney disease.

High levels: If the kidneys function well, there should be no albumin in the urine

Low glomerular filter rate (GFR). This ability is affected by kidney damage. The kidneys should be functioning at 100% or have a GFR 100 Trusted source. A doctor will not diagnose kidney disease if the GFR is below 60%. Kidney disease is defined as a GFR between 15-60%. Below 15% is considered kidney failure.

ESRD is the final stage of kidney disease. Diabetic nephropathy, the most common cause of ESRD in America, is the leading cause. About 40-50% of all cases involving ESRD are related to diabetes. Dialysis is required for someone with ESRD.

The risk can reduce by controlling blood sugar. 

  • Monitoring blood glucose levels and maintaining them within the target range
  • Having a healthy diet low in sugar and salt
  • getting regular exercise
  • Maintaining a healthy weight


Damage to kidneys can cause stress and make it difficult for these vital organs to function properly.

If this happens:

  • The body begins to lose protein through urine
  • The kidneys can’t remove blood products
  • The kidneys are unable to maintain healthy fluid levels within the body

Diabetic kidney disease develops slowly. One study found that a third of diabetic patients have high levels of albumin 15 years Trusted Source. 

A person with diabetes who has not shown any signs or symptoms of nephropathy between 20-25 years ago is at a lower risk of developing it.

Diabetic Nephropathy is less common if someone with diabetes manages their sugar levels well.

High blood sugar levels can increase your risk, Hypertension or high blood pressure can lead to kidney disease.

Other risk factors

There are other risk factors:

Smoking: High levels of inflammation and smoking may cause kidney damage. Although the relationship between smoking and diabetes is not clear, it appears that people who smoke have a higher incidence of diabetes & hypertension and more kidney disease.

Health conditions: Being overweight, obese, insulin resistance, high blood pressure, chronic inflammation, and elevated blood lipids (fats), can all lead to kidney disease.

These risks may be contributing factors or complications to diabetes.

Diabetic neuropathy and diabetic nephropathy are not the same things. They both affect the nervous system. Find out more about peripheral neuropathy and diabetic neuropathy.

Stages and symptoms

A person may not experience any symptoms in the initial stages of diabetic renalpathy. Changes in blood pressure or fluid balance may be already present in diabetic nephropathy. Over time, blood can become contaminated with waste products, which can lead to symptoms.


The GFR is a measure of effective kidney function.

Stage 1: Kidney damage with some loss of function.

 Stage  2: Moderate to severe function loss and a GFR between 30-59%.

Stage  3: Severe loss or GFR of 15-29%

Stage 4: Kidney failure with a GFR below 15%


A person may not feel any symptoms in the beginning stages. They may feel unwell at stage 4 or 5.

  • Swollen feet, ankles, legs, and hands caused by water retention
  • Shortness of breath
  • nausea or vomiting
  • A metallic taste in your mouth

Cardiovascular disease is one of the complications of late-stage renal disease.

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